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Targeting amino acid pathways may represent a promising therapeutic approach to mitigate oxidative stress, control inflammation, and promote recovery in lung injury and fibrosis

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SGLT2 inhibition by empagliflozin promotes fat utilization and browning and attenuates inflammation and insulin resistance by polarizing M2 macrophages in diet-induced obese mice

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In diet-induced obese (DIO) mouse models, NNMT inhibition led to approximately 35% reduction in white adipose tissue mass compared to controls